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DAMAE MEDICAL

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IF WE BRING THE MICROSCOPE DIRECTLY TO YOUR SKIN WITH 3D OPTICAL BIOPSIES, WILL THE MANAGEMENT OF SKIN CANCERS BE IMPROVED?

Skin cancer is the most common and fastest growing form of cancer in the world. The main risk factors for developing skin cancer include exposure to UV radiation, age, sex, ethnicity, occupation, and family history of skin cancer.

It is classified in 2 categories : melanoma, the deadliest form, and carcinoma, the most common type. Each year, skin cancer results in more than 10 thousands deaths, just in Europe. The incidence of the melanoma expands for several decades and doubles all 10 years since 1945 in the world.

Early stage and real-time diagnosis for all skin tumors

BREAKTHROUGH IDEA

DAMAE Medical is a French startup founded in September 2014, located in Paris, which currently employs a multidisciplinary team: advanced research in optics, product design & engineering, computer science, image science, clinical marketing development.

To improve skin cancer diagnosis, DAMAE Medical has developed a novel hand-held imaging device that allows a non-invasive 3D visualization of skin tissues. With a single contact on the skin, the device provides, in real time, images very similar to the histology images. The solution consists in bringing the microscope directly to the patient. The device relies on a unique patented approach combining Optical Coherence Tomography (OCT) with Confocal Microscopy (CM), called LC-OCT (Line-field Confocal OCT). The combination resolution + depth is really was differentiate them from the competition.

schema damae

This technology was invented by Pr. Arnaud Dubois, co-founder and Chief Scientific Officer at DAMAE Medical, and developed in collaboration with CNRS, Institut d'Optique Graduate School and Université Paris-Sud.

LC-OCT is currently used in clinical studies for 3 main uses :

  • Early stage and real-time diagnosis for all skin tumors
  • Definition of accurate presurgical margins for skin surgery
  • Guiding therapy to enable less invasive therapies, follow up treatment response, select best treatment / dosage for a specific patient.

 

BENEFITS TO USE THE 3DEXPERIENCE PLATFORM ON THE CLOUD

Thanks to Solidworks, the LC-OCT device was designed for an easy integration into hospitals, clinics and dermatological private practices. Main product features of LC-OCT device includes an easy-to-use handheld probe with embedded optical and electronics elements. DAMAE Medical is working on industrializing the device and preparing its production scale-up and market introduction. Dassault Systèmes and DAMAE Medical can make this dream happen by providing the 3DEXPERIENCE Cloud Platform to host, share and labellize LC-OCT clinical database.

dermato damae

COLLECTIVE INTELLIGENCE

The development process of a medical device can be rigid, particularly for a start-up. This is why we carry out iterative development cycles during the design and test phases. These principles consist in defining the key assumptions or specifications of the product to be validated, quickly developing a β version of the solution, testing it with market partners (hospitals, laboratories, manufacturers) and then collecting user feedback (on the functionalities, quality, usage, ergonomics, or bugs of the product), implementing them, and starting the loop over until optimal performance is achieved and market expectations are met.

Meet the team

DAMAE Medical has structured an agile flattened hierarchy, composed of high-level talented collaborators, self-directed, motivated, reliable, with a work-team mindset and key competencies to manage high added-value activities of the projects. This organization enables quick decisions, rapid evolutions and paves the way for continuous innovation and reinvention, to provide the market with the best solutions.

  • David  Siret
    David Siret
    CTO
  • Anais Barut
    Anais Barut
    CEO
  • Arnaud Dubois
    Arnaud Dubois
    CSO

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